Analytical Data
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基因名
TADA2L
- Application
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别名
TADA2A; TADA2L; KL04P; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; ADA2-like protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75478
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表达区间
1-443 aa
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氨基酸序列
MDRLGPFSND PSDKPPCRGC SSYLMEPYIK CAECGPPPFF LCLQCFTRGF EYKKHQSDHT YEIMTSDFPV LDPSWTAQEE MALLEAVMDC GFGNWQDVAN QMCTKTKEEC EKHYMKHFIN NPLFASTLLN LKQAEEAKTA DTAIPFHSTD DPPRPTFDSL LSRDMAGYMP ARADFIEEFD NYAEWDLRDI DFVEDDSDIL HALKMAVVDI YHSRLKERQR RKKIIRDHGL INLRKFQLME RRYPKEVQDL YETMRRFARI VGPVEHDKFI ESHALEFELR REIKRLQEYR TAGITNFCSA RTYDHLKKTR EEERLKRTML SEVLQYIQDS SACQQWLRRQ ADIDSGLSPS IPMASNSGRR SAPPLNLTGL PGTEKLNEKE KELCQMVRLV PGAYLEYKSA LLNECNKQGG LRLAQARALI KIDVNKTRKI YDFLIREGYI TKG
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分子量
51.5kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TADA2L (Transcription Adaptor 2-Alpha-Like) is a crucial component of the transcriptional machinery, playing a significant role in the regulation of gene expression. It is a part of the multi-protein complex involved in the transcriptional activation of various genes by facilitating the interaction between transcription factors and the basal transcriptional apparatus. Research on TADA2L has gained momentum due to its implications in cancer biology and other diseases, as dysregulation of transcriptional processes can lead to aberrant cell proliferation and differentiation. Recent studies have highlighted the importance of TADA2L in several oncogenic pathways, suggesting that it may serve as a potential biomarker or therapeutic target in cancer treatment. Furthermore, understanding the structure and function of TADA2L through recombinant protein studies can provide insights into its mechanistic roles in the transcriptional regulation. The production and characterization of TADA2L recombinant protein enable researchers to investigate its interactions with other proteins and its involvement in chromatin remodeling. This research not only enhances our comprehension of transcriptomics but also opens avenues for drug development aimed at modulating TADA2L activity. In summary, TADA2L represents a pivotal focus in molecular biology research due to its overarching influence on transcriptional control and its potential link to various pathologies.
