Analytical Data
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Gene name
WDR37
- Application
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Alternative Names
FLJ40354; KIAA0982; OTTHUMP00000018956; RP11-529L18.2; WD repeat containing Protein 37; WD repeat domain 37; WD repeat-containing Protein 37; Wdr37; WDR37_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y2I8
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Expression Region
1-494 aa
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AA Sequence
MPTESASCST ARQTKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ KLKTTYKAST SKIVSSFKTT TSRAACQLVK EYIGHRDGIW DVSVAKTQPV VLGTASADHT ALLWSIETGK CLVKYAGHVG SVNSIKFHPS EQLALTASGD QTAHIWRYAV QLPTPQPVAD TSISGEDEVE CSDKDEPDLD GDVSSDCPTI RVPLTSLKSH QGVVIASDWL VGGKQAVTAS WDRTANLYDV ETSELVHSLT GHDQELTHCC THPTQRLVVT SSRDTTFRLW DFRDPSIHSV NVFQGHTDTV TSAVFTVGDN VVSGSDDRTV KVWDLKNMRS PIATIRTDSA INRINVCVGQ KIIALPHDNR QVRLFDMSGV RLARLPRSSR QGHRRMVCCS AWSEDHPVCN LFTCGFDRQA IGWNINIPAL LQEK
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Molecular Weight
54.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WDR37, a member of the WD-repeat family of proteins, has garnered attention in recent years due to its potential roles in various cellular processes, including signal transduction, gene regulation, and protein-protein interactions. These proteins are characterized by the presence of multiple WD-repeat domains, which facilitate the formation of multiprotein complexes. Emerging evidence suggests that WDR37 may be implicated in important physiological functions, as well as in pathological conditions, including cancer and neurodegenerative diseases. Specific studies have indicated that WDR37 is involved in regulating cell cycle progression and apoptosis, highlighting its significance in maintaining cellular homeostasis. Additionally, understanding the structural and functional characteristics of WDR37 through recombinant protein studies can illuminate its mechanisms of action and interactions with other cellular components. Researchers are focusing on the recombinant expression and purification of WDR37 to ascertain its functional properties and explore its potential as a therapeutic target. The investigation of WDR37 aims to provide insights into its biological roles and to unravel the complexities of its interactions within the cellular environment, which may ultimately contribute to advancements in disease treatment and prevention strategies.
