Analytical Data
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Gene name
SVOP
- Application
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Alternative Names
SVOP; Synaptic vesicle 2-related protein; SV2-related protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N4V2
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Expression Region
1-548 aa
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AA Sequence
MEEDLFQLRQLPVVKFRRTGESARSEDDTASGEHEVQIEGVHVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSHREWGQEMVGRGMHGAGVTRSNSGSQE
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Molecular Weight
87.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SVOP (Sodium Voltage-Activated Calcium Channel Protein) is a protein that has garnered significant attention in the field of molecular biology and pharmacology due to its potential role in various physiological processes and diseases. Initially identified as a member of the voltage-gated ion channel family, SVOP is believed to be involved in calcium signaling pathways, which are crucial for neurotransmitter release, muscle contraction, and other cellular activities. Research has shown that alterations in SVOP expression and function may be linked to neurological disorders, cardiovascular diseases, and cancer, making it a potential target for therapeutic intervention. The study of SVOP also intersects with the investigation of drug interactions, as its modulation could influence the efficacy of calcium channel blockers and other medications. Despite its significance, the detailed mechanisms of SVOP function and its structural properties remain poorly understood. Thus, the restructuring of SVOP, through techniques like recombinant protein expression and purification, is crucial for elucidating its role in cellular physiology and for exploring its potential in clinical applications. By providing insights into its structure-function relationships, the research on SVOP can pave the way for novel strategies in drug development and disease management, highlighting its relevance in contemporary biomedical research.
