Analytical Data
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基因名
STX19
- Application
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别名
STX19; Syntaxin-19
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N4C7
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表达区间
1-294 aa
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氨基酸序列
MKDRLQELKQ RTKEIELSRD SHVSTTETEE QGVFLQQAVI YEREPVAERH LHEIQKLQES INNLADNVQK FGQQQKSLVA SMRRFSLLKR ESTITKEIKI QAEYINRSLN DLVKEVKKSE VENGPSSVVT RILKSQHAAM FRHFQQIMFI YNDTIAAKQE KCKTFILRQL EVAGKEMSEE DVNDMLHQGK WEVFNESLLT EINITKAQLS EIEQRHKELV NLENQIKDLR DLFIQISLLV EEQGESINNI EMTVNSTKEY VNNTKEKFGL AVKYKKRNPC RVLCCWCCPC CSSK
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分子量
34.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX19, a member of the syntaxin family of proteins, plays a crucial role in membrane trafficking and exocytosis processes within cells. It is primarily involved in the vesicle fusion events necessary for the secretion of various molecules, including neurotransmitters and hormones. Research on STX19 has gained prominence due to its potential implications in various physiological and pathological conditions. For instance, abnormalities in its function are linked to neurodegenerative diseases and metabolic disorders, highlighting the importance of STX19 in maintaining cellular homeostasis. Furthermore, studies have shown that STX19 interacts with other proteins in the SNARE complex, which is vital for synaptic transmission and cellular communication. Understanding the molecular mechanisms underlying STX19 interactions and functions could pave the way for developing therapeutic strategies aimed at restoring normal cellular processes in diseases characterized by dysfunctional membrane trafficking. Additionally, the recombinant production of STX19 enables in-depth structural and functional studies that could elucidate its role in disease and provide insights into potential drug targets. Overall, research on STX19 contributes significantly to the broader field of cell biology and has the potential to inform therapeutic approaches for various disorders linked to the disturbances in membrane trafficking and exocytosis.
