Analytical Data
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基因名
SPTAN1
- Application
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别名
SPTAN1；NEAS；SPTA2；Spectrin alpha chain. non-erythrocytic 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13813
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表达区间
1-580aa
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氨基酸序列
MDPSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFR
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分子量
83.8kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPTAN1, also known as Spectrin Alpha Non-Erythrocytic 1, is a crucial cytoskeletal protein that plays a significant role in maintaining cell structure and function. It is primarily expressed in neural tissues, where it is involved in the organization of the cytoskeleton, influencing cellular processes such as membrane stability, signal transduction, and cell migration. Mutations in the SPTAN1 gene have been linked to various neurological disorders, including epilepsy and developmental delays, highlighting its importance in neural development and function. Researchers have increasingly focused on the study of SPTAN1 recombinant proteins to elucidate its structure-function relationship and understand the molecular mechanisms underlying its role in neurodevelopmental processes. By investigating the properties of SPTAN1 recombinant proteins, scientists aim to uncover potential therapeutic targets for disorders associated with SPTAN1 mutations. Furthermore, the successful expression and characterization of SPTAN1 recombinant proteins in various systems can aid in developing diagnostic tools and therapeutic strategies, providing insight into the pathophysiology of diseases linked to this protein. Overall, the research on SPTAN1 recombinant proteins is essential for advancing our understanding of its biological significance and potential applications in medicine.
