Analytical Data
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基因名
STX18
- Application
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别名
Cell growth inhibiting gene 9 protein; Cell growth-inhibiting gene 9 protein; DKFZp686O15149; STX18; STX18_HUMAN; Syntaxin-18; Ufe1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P2W9
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表达区间
1-335 aa
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氨基酸序列
MAVDITLLFRASVKTVKTRNKALGVAVGGGVDGSRDELFRRSPRPKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS
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分子量
62.48 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX18, or Syntaxin 18, is a member of the syntaxin family of proteins, which are essential components of the SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex involved in membrane trafficking and fusion processes within eukaryotic cells. This protein plays a critical role in the endoplasmic reticulum (ER) and is implicated in various cellular functions, including protein transport, sorting, and secretion. Research has shown that STX18 is involved in maintaining the integrity of the ER membrane and is crucial for the proper functioning of cellular homeostasis. Studies have also indicated its potential link to neurodegenerative diseases and various cancers, making it a significant target for therapeutic intervention. The recombinant production of STX18 has gained attention, as it provides an opportunity to study its structural and functional properties in detail. By utilizing methods such as genetic engineering and expression in suitable host systems, researchers can obtain large quantities of this protein for biochemical assays, structural studies, and functional analyses. Understanding the molecular mechanisms regulated by STX18 may not only unveil its role in fundamental cellular processes but could also lead to novel strategies in treating diseases associated with its dysregulation. Overall, the research surrounding STX18 and its recombinant protein is critical for advancing our knowledge of cellular biology and developing potential therapeutic applications.
