Analytical Data
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Gene name
STRADB
- Application
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Alternative Names
ALS2 chromosome region gene 2; ALS2CR2; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; CALS 21; CALS-21; ILP interacting protein ILPIPA; ILP-interacting protein; ILPIP; ILPIPA; Likely ortholog of mouse polyploidy associated protein kinase; PAPK; PRO1038; Pseudokinase ALS2CR2; STE20-related kinase adapter protein beta; STRAB_HUMAN; STRAD beta; STRADB
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9C0K7
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Expression Region
1-418 aa
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AA Sequence
MSLLDCFCTS RTQVESLRPE KQSETSIHQY LVDEPTLSWS RPSTRASEVL CSTNVSHYEL QVEIGRGFDN LTSVHLARHT PTGTLVTIKI TNLENCNEER LKALQKAVIL SHFFRHPNIT TYWTVFTVGS WLWVISPFMA YGSASQLLRT YFPEGMSETL IRNILFGAVR GLNYLHQNGC IHRSIKASHI LISGDGLVTL SGLSHLHSLV KHGQRHRAVY DFPQFSTSVQ PWLSPELLRQ DLHGYNVKSD IYSVGITACE LASGQVPFQD MHRTQMLLQK LKGPPYSPLD ISIFPQSESR MKNSQSGVDS GIGESVLVSS GTHTVNSDRL HTPSSKTFSP AFFSLVQLCL QQDPEKRPSA SSLLSHVFFK QMKEESQDSI LSLLPPAYNK PSISLPPVLP WTEPECDFPD EKDSYWEF
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Molecular Weight
47.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STRADB (Strabismus-associated protein) is a specialized protein that plays a crucial role in the development and function of the strabismus condition, characterized by misalignment of the eyes. Researchers have increasingly focused on understanding the molecular mechanisms underlying strabismus, as it affects a significant portion of the population and can lead to both visual impairment and psychosocial issues. The study of STRADB has revealed its involvement in various signaling pathways, particularly those associated with neuronal development and the regulation of eye muscle coordination. Moreover, STRADB has been linked to the modulation of synaptic plasticity, which is essential for visual processing and motor control. Given its fundamental role in these processes, there is a growing interest in STRADB as a potential therapeutic target for strabismus and other ocular disorders. Recent advances in genomics, proteomics, and bioinformatics have provided researchers with innovative tools to investigate the structure-function relationships of STRADB, paving the way for novel intervention strategies to restore proper ocular alignment and improve patient outcomes. As the understanding of STRADB expands, it could lead to breakthroughs in both basic science and clinical applications, ultimately enhancing our knowledge of strabismus and contributing to the development of effective treatments. This combination of clinical relevance and biological intrigue makes STRADB a focal point of ongoing research in the fields of ophthalmology and neuroscience.
