Analytical Data
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基因名
TBX4
- Application
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别名
TBX4；T-box transcription factor TBX4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P57082
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表达区间
1-545aa
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氨基酸序列
MLQDKGLSES EEAFRAPGPA LGEASAANAP EPALAAPGLS GAALGSPPGP GADVVAAAAA EQTIENIKVG LHEKELWKKF HEAGTEMIIT KAGRRMFPSY KVKVTGMNPK TKYILLIDIV PADDHRYKFC DNKWMVAGKA EPAMPGRLYV HPDSPATGAH WMRQLVSFQK LKLTNNHLDP FGHIILNSMH KYQPRLHIVK ADENNAFGSK NTAFCTHVFP ETSFISVTSY QNHKITQLKI ENNPFAKGFR GSDDSDLRVA RLQSKEYPVI SKSIMRQRLI SPQLSATPDV GPLLGTHQAL QHYQHENGAH SQLAEPQDLP LSTFPTQRDS SLFYHCLKRR DGTRHLDLPC KRSYLEAPSS VGEDHYFRSP PPYDQQMLSP SYCSEVTPRE ACMYSGSGPE IAGVSGVDDL PPPPLSCNMW TSVSPYTSYS VQTMETVPYQ PFPTHFTATT MMPRLPTLSA QSSQPPGNAH FSVYNQLSQS QVRERGPSAS FPRERGLPQG CERKPPSPHL NAANEFLYSQ TFSLSRESSL QYHSGMGTVE NWTDG
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TBX4, a member of the T-box family of transcription factors, plays a crucial role in various developmental processes, particularly in limb and genitourinary system formation. Mutations in the TBX4 gene have been linked to congenital disorders such as small patella syndrome and other skeletal anomalies, highlighting its importance in proper limb development. Recent studies have begun to explore the functional mechanisms of TBX4 at the molecular level, revealing its involvement in the regulation of gene expression during embryogenesis. These findings underscore the need for the production and characterization of recombinant TBX4 protein, which can provide insights into its precise functions and interactions within the developmental pathways. The generation of TBX4 recombinant protein facilitates further exploration of its structural and functional properties, enabling researchers to investigate how TBX4 influences cellular processes and contributes to phenotypic outcomes. Moreover, understanding TBX4's role at the protein level could lead to advancements in therapeutic strategies for conditions associated with its dysregulation. Thus, the study of TBX4 recombinant protein is not only pivotal for basic developmental biology but also holds potential implications for regenerative medicine and genetic disorder interventions.
