Analytical Data
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Gene name
STAG3L3
- Application
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Alternative Names
STAG3L3; STAG3-like protein 3; Stromal antigen 3-like protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P0CL85
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Expression Region
1-134 aa
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AA Sequence
MIFSMLRKLP KVTCRDVLPE IRAICIEEIG CWMQSYSTSF LTDSYLKYIG WTLHDKHREV RVKCVKALKG LYGNRDLTAR LELFTGCFKD WMVSMIMDRE YSVAVEAVRL LILILKNMEG VLMDVDCESV YPIV
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Molecular Weight
15.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STAG3L3, a member of the Stag family of proteins, has emerged as a crucial player in various cellular processes, including transcription regulation, cell cycle control, and chromosome segregation. Research on STAG3L3 has gained momentum due to its potential implications in cancer biology and developmental disorders. This protein acts as a cohesin-associated factor, participating in the formation of chromosome cohesin complexes, which are essential for maintaining genomic stability during cell division. Dysregulation of STAG3L3 has been linked to tumorigenesis, as it may influence the expression of genes involved in cell proliferation and apoptosis. Additionally, studies have shown that STAG3L3 interacts with several transcription factors, further highlighting its role in regulating gene expression. Understanding the structure and function of STAG3L3, particularly through the development and characterization of recombinant protein, can provide insights into its biological mechanisms and potential as a therapeutic target. The research surrounding STAG3L3 is not only significant for elucidating its role in normal cellular functions but also for uncovering its contributions to disease processes, paving the way for innovative approaches in cancer treatment and genetic therapies.
