Analytical Data
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基因名
DLX5
- Application
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别名
DLX5Homeobox protein DLX-5
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56178
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表达区间
1-289aa
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氨基酸序列
MTGVFDRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTLY
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分子量
57.53 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DLX5 is a member of the distal-less homeobox (DLX) gene family, which plays a crucial role in embryonic development and the regulation of various biological processes. It is primarily involved in the development of the face and the forebrain, contributing to the formation of craniofacial structures and neuronal differentiation. Abnormalities in DLX5 expression have been linked to various developmental disorders, including isolated cleft lip and palate, which highlights its significance in craniofacial biology. Additionally, DLX5 has been implicated in the regulation of osteogenic differentiation, making it a point of interest in bone development research and potential therapeutic applications for bone-related diseases. The study of recombinant DLX5 protein provides insights into its functional properties and mechanisms of action, enabling researchers to investigate its interactions with other molecular players involved in developmental pathways. By expressing and purifying the DLX5 protein in a recombinant system, researchers aim to dissect its structure-function relationship, explore its binding affinities, and evaluate its downstream effects on gene expression. This research not only enhances our understanding of DLX5's role in normal development but also holds promise for identifying therapeutic targets in congenital disorders and regenerative medicine. The development of methods for robust recombinant DLX5 production is vital for advancing the field and facilitating further studies on its biological implications. Overall, the research surrounding DLX5 recombinant protein is a crucial step towards elucidating its function in development, disease, and potential therapeutic interventions.












