Cat: PA2000-7141

Recombinant Human DLX2 Protein,GST

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Analytical Data

  • 基因名

    DLX2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    DLX 2; DLX2; DYLX 2; DYLX2; Dyslexia susceptibility 2; Dyslexia-associated protein KIAA0319; DYX 2; DYX2; K0319_HUMAN; Kiaa0319; MGC176717

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q5VV43

  • 表达区间

    1-328aa

  • 氨基酸序列

    MTGVFDSLVADMHSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLHKPQESPTLPVSTATDSSYYTNQQHPAGGGGGGGSPYAHMGSYQYQASGLNNVPYSAKSSYDLGYTAAYTSYAPYGTSSSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFGVPQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGNYPWYHQTSGSASHLQATAPLLHPTQTPQPHHHHHHHGGGGAPVSAGTIF

  • 分子量

    61.82 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

DLX2 is a member of the distal-less (DLX) homeobox gene family, which plays a crucial role in embryonic development, particularly in the formation of the craniofacial region, forebrain, and limb structures. Its significance in developmental biology stems from its involvement in the regulation of neural and mesodermal differentiation, making it a key player in the formation of both the central nervous system and various tissues. Research has shown that DLX2 is essential for the proper development of GABAergic interneurons, which are vital for establishing balance within neural circuits. Mutations or dysregulation of DLX2 have been linked to various congenital disorders and neurodevelopmental conditions, highlighting its potential as a therapeutic target. The study of DLX2 recombinant protein offers insights into its functional mechanisms, interactions with other proteins, and its role in signaling pathways involved in cell differentiation and proliferation. 


By generating DLX2 recombinant proteins, researchers can perform detailed biochemical and biophysical analyses, facilitating the identification of binding partners and elucidating the protein's role in developmental processes. Understanding the structure and function of DLX2 can also aid in uncovering its contributions to disease pathology, thus providing a foundation for developing targeted therapies. In summary, the study of DLX2 recombinant protein encompasses a significant area of research that links basic developmental biology with potential clinical applications, aiming to unravel the complexities of neural development and associated disorders.


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