Analytical Data
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Gene name
SPE39
- Application
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Alternative Names
SPE39；C14orf133；SPE39；VIPAR；Spermatogenesis-defective Protein 39 homolog
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H9C1
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Expression Region
1-493aa
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AA Sequence
MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDDDDLERVSWSGEPVGSISWSIRETAGNSGSTHEGREQLKSRNSFSSYAQLPKPTSTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRKGKVCSLERFRSLQDKLQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPDKRKEFLKTCVGLPFSAEDSAHIQDHYTLLERQIIIEANDRHLESAGQTEIFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYVLTALAARAKLRAWNDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNNAPVQILQEYVNLVEDVDTKLNLATKFKCHDVVIDTYRDLKDRQQLLAYRSKVDKGSAEEEKIDALLSSSQIRWKN
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Molecular Weight
73.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPE39, a protein derived from the pathogen *Streptococcus pneumoniae*, has garnered significant attention in the field of molecular biology and infectious disease research due to its role in bacterial virulence and host interaction. As a critical component of the bacterium’s arsenal, SPE39 is believed to be involved in evading the host's immune response, thus facilitating infection and persistence within the host. Research into SPE39 encompasses its structural properties, biological functions, and potential as a target for therapeutic interventions. Given the increasing antibiotic resistance observed in many strains of *S. pneumoniae*, understanding the mechanisms through which SPE39 operates is crucial for developing novel treatment strategies. Scientists are particularly interested in elucidating the molecular pathways that SPE39 influences, as this could lead to breakthroughs in vaccine development and the creation of new antimicrobial agents. Additionally, the study of SPE39’s interactions with host immune cells can provide insights into the broader context of bacterial pathogenesis and host-microbe dynamics. By dissecting the role of SPE39, researchers aim to contribute to a more comprehensive understanding of *S. pneumoniae* infections and ultimately improve clinical outcomes for affected patients.
