Analytical Data
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Gene name
SPRR1B
- Application
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Alternative Names
14.9 kDa pancornulin; Cornifin ; Cornifin B; Cornifin-B; CornifinB; GADD33; MGC61901; Small proline rich protein IB; Small proline-rich protein IB; SPR-IB; SPR1B_HUMAN; SPRIB; SPRR1; SPRR1B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P22528
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Expression Region
1-89aa
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AA Sequence
MSSQQQKQPC TPPPQLQQQQ VKQPCQPPPQ EPCIPKTKEP CHPKVPEPCH PKVPEPCQPK VPEPCHPKVP EPCPSIVTPA PAQQKTKQK
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Molecular Weight
9.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPRR1B (Small Proline-Rich Protein 1B) is a member of the small proline-rich protein family, which plays a critical role in various biological processes, including cell differentiation, proliferation, and response to stress. Research on SPRR1B has gained momentum due to its potential involvement in skin-related disorders, such as psoriasis and cancer. It is predominantly expressed in epithelial tissues, suggesting a significant role in maintaining skin barrier function and modulating the inflammatory response. Recent studies have indicated that SPRR1B may enhance keratinocyte migration and skin regeneration, making it a focal point for understanding wound healing mechanisms. Additionally, its expression levels are altered in pathological conditions, hinting at its potential as a biomarker for skin diseases. The recombinant form of SPRR1B has been developed for functional studies, allowing researchers to explore its properties and therapeutic applicability. Investigating SPRR1B's role at the molecular level may unveil novel targets for intervention in skin diseases, thereby contributing to the development of new treatments and improving patient outcomes. Overall, the research on SPRR1B and its recombinant protein aligns with a broader interest in understanding the underlying mechanisms of skin health and disease.
