Analytical Data
-
基因名
SPRR1B
- Application
-
别名
14.9 kDa pancornulin; Cornifin ; Cornifin B; Cornifin-B; CornifinB; GADD33; MGC61901; Small proline rich protein IB; Small proline-rich protein IB; SPR-IB; SPR1B_HUMAN; SPRIB; SPRR1; SPRR1B
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P22528
-
表达区间
1-89aa
-
氨基酸序列
MSSQQQKQPC TPPPQLQQQQ VKQPCQPPPQ EPCIPKTKEP CHPKVPEPCH PKVPEPCQPK VPEPCHPKVP EPCPSIVTPA PAQQKTKQK
-
分子量
9.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human DLGAP4 Protein，GST
Cat：PA2000-7139
Recombinant Human NOTCH3 Protein，His
Cat：PA1000-7904
Recombinant Human CHMP4B Protein，His
Cat：PA2000-3482
Protein Description
SPRR1B (Small Proline-Rich Protein 1B) is a member of the small proline-rich protein family, which plays a critical role in various biological processes, including cell differentiation, proliferation, and response to stress. Research on SPRR1B has gained momentum due to its potential involvement in skin-related disorders, such as psoriasis and cancer. It is predominantly expressed in epithelial tissues, suggesting a significant role in maintaining skin barrier function and modulating the inflammatory response. Recent studies have indicated that SPRR1B may enhance keratinocyte migration and skin regeneration, making it a focal point for understanding wound healing mechanisms. Additionally, its expression levels are altered in pathological conditions, hinting at its potential as a biomarker for skin diseases. The recombinant form of SPRR1B has been developed for functional studies, allowing researchers to explore its properties and therapeutic applicability. Investigating SPRR1B's role at the molecular level may unveil novel targets for intervention in skin diseases, thereby contributing to the development of new treatments and improving patient outcomes. Overall, the research on SPRR1B and its recombinant protein aligns with a broader interest in understanding the underlying mechanisms of skin health and disease.
