Analytical Data
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Gene name
DIMT1L
- Application
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Alternative Names
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; 18S rRNA dimethylase; DIM1; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae); DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1 like ; DIM1 dimethyladenosine transferase 1-like; Dimethyladenosine transferase; DIMT1; DIMT1_HUMAN; DIMT1L; HSA9761; HUSSY5; N''-adenosyl(rRNA) dimethyltransferase; Probable 18S rRNA (adenine(1779) N(6)/adenine(1780) N(6)) dimethyltransferase; Probable 18S rRNA dimethylase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UNQ2
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Expression Region
1-313aa
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AA Sequence
MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
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Molecular Weight
51.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DIMT1L (DIM-like protein 1-like) is a protein that has garnered attention due to its intriguing role in various biological processes, including cellular stress response and RNA metabolism. It is associated with the regulation of gene expression and protein synthesis, making it a key player in understanding cellular functions and adaptations. Recent studies have indicated that DIMT1L may be involved in the modulation of immune responses and developmental processes, suggesting its potential implications in diseases such as cancer and autoimmune disorders. The interest in recombinant DIMT1L protein arises from the desire to elucidate its structure-function relationship and to explore its potential as a therapeutic target. By producing and studying recombinant DIMT1L, researchers aim to unravel its molecular mechanisms and interactions within cellular pathways. This research not only contributes to a deeper understanding of DIMT1L's biological roles but also paves the way for potential applications in biotechnology and medicine, reinforcing the significance of this protein in both fundamental and applied sciences. Through advanced techniques in recombinant protein production and characterization, scientists are positioned to investigate DIMT1L with greater precision, thereby shedding light on its functional importance in health and disease.











