Analytical Data
-
Gene name
KLF15
- Application
-
Alternative Names
KLF15；KKLF；Krueppel-like factor 15
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9UIH9
-
Expression Region
1-416aa
-
AA Sequence
MVDHLLPVDENFSSPKCPVGYLGDRLVGRRAYHMLPSPVSEDDSDASSPC SCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGSSIGASS GPVAWGPWRRAAAPVKGEHFCLPEFPLGDPDDVPRPFQPTLEEIEEFLEE NMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGAS AGGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPGQAPENVKVAQ LLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGP AGLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKP FACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHI KVHRFPRSSRSVRSVN
-
Molecular Weight
70 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KLF15, or Krüppel-like factor 15, is a pivotal transcription factor belonging to the KLF family, known for its significant role in regulating various biological processes, including cell differentiation, proliferation, and metabolism. Research has shown that KLF15 is particularly important in cardiovascular health, glucose homeostasis, and lipid metabolism, making it a key player in diseases such as diabetes and heart failure. Furthermore, KLF15 is implicated in the regulation of gene expression in response to hormonal signals, such as insulin, which is crucial for maintaining metabolic stability. Despite its importance, the mechanisms underlying KLF15's function and its potential therapeutic applications remain inadequately explored. The production and study of recombinant KLF15 protein can provide critical insights into its structure-function relationships and regulatory pathways. By generating this protein in a controlled laboratory setting, researchers can investigate KLF15's interactions with other molecular partners and assess its effects on gene expression in various cell types. Additionally, understanding the post-translational modifications of KLF15 through recombinant methodologies may enhance our knowledge of its biological roles in health and disease. Overall, the study of recombinant KLF15 is expected to advance our understanding of its involvement in metabolic processes and identify potential targets for therapeutic intervention in metabolic disorders.
