Analytical Data
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基因名
KLF15
- Application
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别名
KLF15；KKLF；Krueppel-like factor 15
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UIH9
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表达区间
1-416aa
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氨基酸序列
MVDHLLPVDENFSSPKCPVGYLGDRLVGRRAYHMLPSPVSEDDSDASSPC SCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGSSIGASS GPVAWGPWRRAAAPVKGEHFCLPEFPLGDPDDVPRPFQPTLEEIEEFLEE NMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGAS AGGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPGQAPENVKVAQ LLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGP AGLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKP FACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHI KVHRFPRSSRSVRSVN
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分子量
70 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLF15, or Krüppel-like factor 15, is a pivotal transcription factor belonging to the KLF family, known for its significant role in regulating various biological processes, including cell differentiation, proliferation, and metabolism. Research has shown that KLF15 is particularly important in cardiovascular health, glucose homeostasis, and lipid metabolism, making it a key player in diseases such as diabetes and heart failure. Furthermore, KLF15 is implicated in the regulation of gene expression in response to hormonal signals, such as insulin, which is crucial for maintaining metabolic stability. Despite its importance, the mechanisms underlying KLF15's function and its potential therapeutic applications remain inadequately explored. The production and study of recombinant KLF15 protein can provide critical insights into its structure-function relationships and regulatory pathways. By generating this protein in a controlled laboratory setting, researchers can investigate KLF15's interactions with other molecular partners and assess its effects on gene expression in various cell types. Additionally, understanding the post-translational modifications of KLF15 through recombinant methodologies may enhance our knowledge of its biological roles in health and disease. Overall, the study of recombinant KLF15 is expected to advance our understanding of its involvement in metabolic processes and identify potential targets for therapeutic intervention in metabolic disorders.
