Analytical Data
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基因名
KLF2
- Application
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别名
KLF2；LKLF；Krueppel-like factor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5W3
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表达区间
1-355aa
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氨基酸序列
MALSEPILPS FSTFASPCRE RGLQERWPRA EPESGGTDDD LNSVLDFILS MGLDGLGAEA APEPPPPPPP PAFYYPEPGA PPPYSAPAGG LVSELLRPEL DAPLGPALHG RFLLAPPGRL VKAEPPEADG GGGYGCAPGL TRGPRGLKRE GAPGPAASCM RGPGGRPPPP PDTPPLSPDG PARLPAPGPR ASFPPPFGGP GFGAPGPGLH YAPPAPPAFG LFDDAAAAAA ALGLAPPAAR GLLTPPASPL ELLEAKPKRG RRSWPRKRTA THTCSYAGCG KTYTKSSHLK AHLRTHTGEK PYHCNWDGCG WKFARSDELT RHYRKHTGHR PFQCHLCDRA FSRSDHLALH MKRHM
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLF2, or Krüppel-like factor 2, is a key transcription factor that plays a critical role in various biological processes, including vascular biology, inflammation, and immune response regulation. It is widely recognized for its protective effects in endothelial cells and its involvement in maintaining vascular homeostasis. Research has shown that KLF2 is essential for modulating the expression of genes related to cell adhesion, migration, and survival, making it a significant player in cardiovascular health. The recombinant protein of KLF2 has garnered interest due to its potential therapeutic applications, particularly in regenerative medicine and tissue engineering. By studying KLF2 recombinant proteins, researchers aim to understand its mechanism of action more thoroughly, explore its role in therapeutic angiogenesis, and evaluate its implications in diseases such as atherosclerosis and diabetes. Additionally, generating KLF2 as a recombinant protein allows scientists to investigate its interactions with other proteins and cellular pathways, paving the way for novel interventions targeting cardiovascular and inflammatory diseases. This growing body of research holds promise not only for elucidating KLF2's biological functions but also for developing innovative strategies to harness its potential in clinical settings.
