Analytical Data
-
基因名
PITHD1
- Application
-
别名
PITHD1；C1orf128；PITH domain-containing Protein 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9GZP4
-
表达区间
1-211aa
-
氨基酸序列
MSHGHSHGGGGCRCAAEREEPPEQRGLAYGLYLRIDLERLQCLNESREGSGRGVFKPWEERTDRSKFVESDADEELLFNIPFTGNVKLKGIIIMGEDDDSHPSEMRLYKNIPQMSFDDTEREPDQTFSLNRDLTGELEYATKISRFSNVYHLSIHISKNFGADTTKVFYIGLRGEWTELRRHEVTICNYEASANPADHRVHQVTPQTHFIS
-
分子量
31.6 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PITHD1, or phosphatidylinositol phosphate phosphatase related to the inositol 1,4,5-trisphosphate receptor, is a protein that has garnered attention in the field of molecular and cellular biology due to its potential roles in signal transduction and cellular processes. It is known to be involved in phosphoinositide metabolism, influencing various cellular functions such as membrane trafficking, cytoskeletal dynamics, and apoptosis. Research into PITHD1 has revealed that it can modulate the activity of phosphoinositide-dependent signaling pathways, which are crucial for numerous physiological processes, including cell growth, differentiation, and survival. Dysregulation of PITHD1 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. Current studies focus on the structural characterization of PITHD1 through recombinant protein expression techniques, enabling a deeper understanding of its functional mechanisms and interactions with other cellular components. Understanding PITHD1's role at the molecular level may provide insights into its implications in health and disease, paving the way for novel therapeutic strategies.
