Analytical Data
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Gene name
DCAMKL3
- Application
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Alternative Names
BC056929; C730036H08; CLICK I and II related; CLr; Click I II related; CLR; Dcamkl3; DCDC3C; DCK3; Dclk3; DCLK3_HUMAN; Doublecortin and CaM kinase like 3; Doublecortin domain-containing protein 3C; Doublecortin-like and CAM kinase-like 3
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9C098
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Expression Region
1-576aa
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AA Sequence
MRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHARGEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRTRSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKEKKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDRKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
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Molecular Weight
92.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DCAMKL3, or Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Non-integrin 3, is a member of the DCAMKL family that is predominantly expressed in dendritic cells and is implicated in various signaling pathways related to immune responses. Research on DCAMKL3 has gained traction due to its potential role in modulating immune cell functions, specifically in the context of immune tolerance and response to pathogens. Studies suggest that DCAMKL3 may facilitate the interaction between dendritic cells and T cells, influencing T cell activation and differentiation. Its unique expression pattern and functional significance in immune regulation make it a promising target for therapeutic interventions in autoimmune diseases, allergic reactions, and cancers. Furthermore, recombinant DCAMKL3 protein has emerged as an important tool in elucidating its biological functions and pathways, allowing researchers to explore its mechanisms of action in greater detail. The production of this protein through recombinant DNA technology is crucial for advancing our understanding of its role in immune modulation and may lead to innovative strategies for enhancing immune therapies. Overall, the investigation into DCAMKL3 and its recombinant protein serves as a vital step in uncovering the complexities of immune system regulation and potential clinical applications.
