Analytical Data
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基因名
NUP37
- Application
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别名
NUP37；Nucleoporin Nup37
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NFH4
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表达区间
1-326aa
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氨基酸序列
MKQDASRNAA YTVDCEDYVH VVEFNPFENG DSGNLIAYGG NNYVVIGTCT FQEEEADVEG IQYKTLRTFH HGVRVDGIAW SPETRLDSLP PVIKFCTSAA DMKIRLFTSD LQDKNEYKVL EGHTDFINGL VFDPKEGQEI ASVSDDHTCR IWNLEGVQTA HFVLHSPGMS VCWHPEETFK LMVAEKNGTI RFYDLLAQQA ILSLESEQVP LMSAHWCLKN TFKVGAVAGN DWLIWDITRS SYPQNKRPVH MDRACLFRWS TISENLFATT GYPGKMASQF QIHHLGHPQP ILMGSVAVGS GLSWHRTLPL CVIGGDHKLL FWVTEV
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分子量
36.7kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NUP37 is a crucial component of the nuclear pore complex (NPC), which plays a significant role in nucleocytoplasmic transport, mediating the exchange of molecules between the nucleus and the cytoplasm. The study of NUP37 recombinant protein has gained attention due to its potential implications in various cellular processes, including gene expression regulation and signal transduction. Dysregulation of NUP37 has been linked to several diseases, including cancer, highlighting its importance in cellular health and disease mechanisms. Furthermore, the recombinant production of NUP37 allows for detailed biochemical and biophysical characterization, facilitating the understanding of its structural properties and interaction with other nuclear pore components. This information could pave the way for the development of therapeutic strategies targeting NPC-related disorders. Additionally, studying NUP37 in various model systems enhances our understanding of the evolutionary conservation of nucleocytoplasmic transport mechanisms across species. The recombinant protein serves as a valuable tool for elucidating the functional roles of NUP37 and its interactions, thereby contributing to a broader comprehension of the complex regulatory networks governing cellular homeostasis.
