Analytical Data
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Gene name
CPNE5
- Application
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Alternative Names
A830083G22Rik; Copine 5; Copine V; Copine-5; Copine5; CopineV; COPN 5; COPN5; CPN 5; CPN5; CPNE 5; CPNE5; CPNE5_HUMAN; DKFZp666C234; KIAA1599; MGC47475; OTTHUMP00000039675
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HCH3
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Expression Region
1-301aa
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AA Sequence
MKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI
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Molecular Weight
59 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CPNE5 (Copine 5) is a member of the copine protein family, which is known for its role in calcium-dependent phospholipid binding and involvement in various cellular processes, including signal transduction and membrane trafficking. The study of CPNE5 has garnered increasing attention due to its potential implications in neurological functions and diseases. Notably, CPNE5 is expressed in the brain and has been implicated in synaptic plasticity, making it a candidate for studying neurodevelopmental disorders and neurodegenerative diseases. Moreover, research has indicated that mutations or dysregulation of CPNE5 may contribute to pathologies such as Alzheimer’s disease, emphasizing the importance of understanding its molecular mechanisms. The recombinant expression of CPNE5 allows researchers to obtain the protein in sufficient quantities for biochemical and structural studies, facilitating investigations into its functional roles and interactions with other cellular components. Overall, the study of CPNE5 and its recombinant protein form contributes to our understanding of its biological significance and potential as a therapeutic target in various neurological conditions.
