Analytical Data
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Gene name
HRG
- Application
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Alternative Names
HRG；Histidine-rich glycoProtein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P04196
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Expression Region
19-525aa
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AA Sequence
VSPTDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDRVENTTVYY LVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQD LRVIDFNCTTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEE NDDFASFRVDRIERVARVRGGEGTGYFVDFSVRNCPRHHFPRHPNVFGFC RADLFYDVEALDLESPKNLVINCEVFDPQEHENINGVPPHLGHPFHWGGH ERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPP LLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHA HHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCD PPPHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGE VLPLPEANFPSFPLPHHKHPLKPDNQPFPQSVSESCPGKFKSGFPQVSMF FTHTFPK
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HRG (Haptoglobin-related protein) is an intriguing member of the lipocalin family with significant implications in various biological processes and disease mechanisms. Initially identified as a protein involved in the transport of hemoglobin and associated with the immune response, HRG has garnered interest due to its dual role as both a protective molecule and a potential biomarker in various pathologies, including cancer and cardiovascular diseases. Recent studies have highlighted its involvement in inflammatory processes, influencing cell proliferation and apoptosis, thereby suggesting its pivotal role in tumor progression and metastasis. Furthermore, HRG's unique structure, which allows it to bind different ligands, supports its function in modulating immune responses and provides insights into its potential therapeutic applications. The ongoing research into HRG restructuring and its interactions at the molecular level seeks to enhance our understanding of its biological significance, paving the way for innovative strategies in diagnostics and treatment. As scientists continue to unravel the complexities of HRG, the potential for this protein to serve as a target for novel therapies remains an exciting area of investigation that may lead to breakthroughs in the management of various diseases.
