Analytical Data
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基因名
CEECAM1
- Application
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别名
CEECAM1 ; Cercam; Cerebral cell adhesion molecule; Cerebral endothelial cell adhesion molecule 1; Cerebral endothelial cell adhesion molecule; GLT25D3 ; Glycosyltransferase 25 domain containing 3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5T4B2
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表达区间
1-517aa
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氨基酸序列
MLQEWLAAVGDDYAAVVWRPEGEPRFYPDEEGPKHWTKERHQFLMELKQEALTFARNWGADYILFADTDNILTNNQTLRLLMGQGLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRRGCFRVPMVHSTFLASLRAEGADQLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNEHRYGYMNVPVKSHQGLEDERVNFIHLILEALVDGPRMQASAHVTRPSKRPSKIGFDEVFVISLARRPDRRERMLASLWEMEISGRVVDAVDGWMLNSSAIRNLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVARGLARVLVFEDDVRFESNFRGRLERLMEDVEAEKLSWDLIYLGRKQVNPEKETAVEGLPGLVVAGYSYWTLAYALRLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLVAFSAQPLLAAPTHYAGDAEWLSDTETSSPWDDDSGRLISWSGSQKTLRSPRLDLTGSSGHSLQPQPRDEL
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分子量
85.5 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CEECAM1, or Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1, is a member of the CEACAM family, which plays a significant role in cellular adhesion and signaling. It is primarily expressed in epithelial tissues and has been implicated in various physiological and pathological processes, including cancer progression, immune response modulation, and cell differentiation. Research has shown that CEECAM1 is involved in tumorigenesis, contributing to the metastatic potential of cancer cells by facilitating cell-cell interactions and influencing immune evasion. The study of CEECAM1 as a recombinant protein is crucial for understanding its structural and functional properties, as well as its potential as a therapeutic target. By producing CEECAM1 as a recombinant protein, researchers can conduct detailed investigations into its binding characteristics, interactions with other biomolecules, and role in cellular pathways. Furthermore, the recombinant form allows for the development of specific antibodies or inhibitors that may have diagnostic or therapeutic applications in oncology and immunology. As the scientific community continues to explore CEECAM1's multifaceted role in disease, its study as a recombinant protein promises to provide valuable insights that could lead to novel treatment strategies.












