Analytical Data
-
基因名
SAFB2
- Application
-
别名
DKFZP779C1727; HAP; HET; hsp27 ere tata binding; KIAA0138 ; SAF B; SAF B2 ; SAF-B2; SAFB; SAFB1; SAFB2; SAFB2_HUMAN; Scaffold attachment factor B2
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q14151
-
表达区间
1-528 aa
-
氨基酸序列
MAETLPGSGDSGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERLKKAVKEEGQDPDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASLENLQNMGMMDMSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEHAVDGEGFKNTLETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEM
-
分子量
83.6 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SAFB2 (SAF-B2) is a member of the Scaffold Attachment Factor (SAF) family, involved in various cellular processes, including gene regulation, RNA processing, and chromatin remodeling. Its role in nuclear mRNA export and its interactions with proteins involved in transcriptional regulation make it a critical player in maintaining cellular homeostasis. Recent studies have identified SAFB2 as a potential biomarker in several diseases, including cancer, where it has been linked to tumor progression and poor prognosis. The understanding of SAFB2's molecular mechanisms and its interactions with other proteins is still evolving, presenting challenges due to its multifunctional nature. The recombinant expression and characterization of SAFB2 protein are essential for elucidating its structure-function relationships and for developing therapeutic strategies targeting its pathways. Researchers aim to produce high-purity, functional SAFB2 recombinant protein to study its role in cellular mechanisms and its potential interplay with therapeutic agents. Additionally, these studies can provide insights into signal transduction pathways that may be altered in disease contexts and help identify novel targets for intervention in diseases where SAFB2 plays a significant role. Consequently, understanding SAFB2 not only contributes to the basic knowledge of cellular biology but also opens avenues for innovative therapeutic approaches in diseases associated with its dysregulation.
