Analytical Data
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Gene name
CCDC127
- Application
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Alternative Names
CCDC127Coiled-coil domain-containing Protein 127
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96BQ5
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Expression Region
1-260aa
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AA Sequence
MNNLNDPPNW NIRPNSRADG GDGSRWNYAL LVPMLGLAAF RWIWSRESQK EVEKEREAYR RRTAAFQQDL EAKYHAMISE NRRAVAQLSL ELEKEQNRTA SYREALISQG RKLVEEKKLL EQERAQVMQE KRQVQPLRSA YLSCLQREEN WQRRARLLLK EFEAVLTERQ NIYCSLFLPR SKRLEIEKSL LVRASVDPVA ADLEMAAGLT DIFQHDTYCG DVWNTNKRQN GRLMWLYLKY WELVVELKKF KRVEEAILEK
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Molecular Weight
57.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC127, or Coiled-Coil Domain Containing 127, is a protein encoded by the CCDC127 gene, which has been implicated in various cellular processes related to animal development and disease. Research has suggested that CCDC127 plays a significant role in the regulation of cell cycle progression and differentiation, making it a potential candidate for studying abnormal cell growth associated with cancer. Its coiled-coil structure indicates a role in protein-protein interactions, further underscoring its importance in cellular signaling pathways. Additionally, studies have linked mutations in the CCDC127 gene to specific genetic disorders, highlighting the relevance of this protein in understanding human health and disease. Recent advances in recombinant protein technology have enabled the production of CCDC127 in vitro, facilitating detailed functional and structural studies. By investigating the biochemical properties and interactions of CCDC127, researchers aim to elucidate its role in cellular mechanics and its potential as a therapeutic target. Overall, the study of CCDC127 presents an exciting opportunity to contribute to the broader understanding of coiled-coil domain-containing proteins and their implications in biological processes.
