Analytical Data
-
Gene name
MEL1
- Application
-
Alternative Names
MEL1；KIAA1675；MEL1；PFM13；Histone-lysine N-methyltransferase PRDM16
-
Species
E.coli
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P04824
-
Expression Region
19-471aa
-
AA Sequence
VSPSYNGLGLTPQMGWDNWNTFACDVSEQLLLDTADRISDLGLKDMGYKYIILDDCWSSGRDSDGFLVADEQKFPNGMGHVADHLHNNSFLFGMYSSAGEYTCAGYPGSLGREEEDAQFFANNRVDYLKYDNCYNKGQFGTPEISYHRYKAMSDALNKTGRPIFYSLCNWGQDLTFYWGSGIANSWRMSGDVTAEFTRPDSRCPCDGDEYDCKYAGFHCSIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGANVNNLKASSYSIYSQASVIAINQDSNGIPATRVWRYYVSDTDEYGQGEIQMWSGPLDNGDQVVALLNGGSVSRPMNTTLEEIFFDSNLGSKKLTSTWDIYDLWANRVDNSTASAILGRNKTATGILYNATEQSYKDGLSKNDTRLFGQKIGSLSPNAILNTTVPAHGIAFYRLRPSS
-
Molecular Weight
52.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MEL1, a member of the melatonin receptor family, has garnered significant attention in recent years due to its pivotal role in various physiological processes across different species. Initially identified in plants, MEL1 has been linked to the regulation of circadian rhythms, stress responses, and developmental processes. In animals, particularly in vertebrates, MEL1 is believed to mediate the effects of melatonin, a hormone that regulates sleep-wake cycles and seasonal biological rhythms. Research has shown that MEL1 may influence immune responses, reproductive behaviors, and metabolic regulation, highlighting its potential therapeutic implications. The growing interest in MEL1 is driven by its relevance in understanding both fundamental biological mechanisms and practical applications, such as enhancing agricultural resilience in crops and developing novel therapies for sleep disorders and mood regulation in humans. Recent advancements in recombinant protein technology have facilitated the production and characterization of MEL1, enabling researchers to explore its structure-function relationships and interactions with signaling pathways. Consequently, MEL1 continues to be a focal point of research, promising to uncover new insights into its multifaceted roles in health and disease.
