Analytical Data
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Gene name
RHOBTB1
- Application
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Alternative Names
1700008H16Rik; 3110048G13Rik; AI173445; AI573858; AV350930; KIAA0740; MGC107538; MGC33059; MGC33841 ; OTTHUMP00000019662 ; OTTHUMP00000019663 ; RHBT1_HUMAN; Rho related BTB domain containing 1; Rho related BTB domain containing protein 1; Rho-related BTB domain-containing protein 1; Rhobtb1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O94844
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Expression Region
1-696 aa
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AA Sequence
MDADMDYERP NVETIKCVVV GDNAVGKTRL ICARACNTTL TQYQLLATHV PTVWAIDQYR VCQEVLERSR DVVDEVSVSL RLWDTFGDHH KDRRFAYGRS DVVVLCFSIA NPNSLNHVKS MWYPEIKHFC PRTPVILVGC QLDLRYADLE AVNRARRPLA RPIKRGDILP PEKGREVAKE LGLPYYETSV FDQFGIKDVF DNAIRAALIS RRHLQFWKSH LKKVQKPLLQ APFLPPKAPP PVIKIPECPS MGTNEAACLL DNPLCADVLF ILQDQEHIFA HRIYLATSSS KFYDLFLMEC EESPNGSEGA CEKEKQSRDF QGRILSVDPE EEREEGPPRI PQADQWKSSN KSLVEALGLE AEGAVPETQT LTGWSKGFIG MHREMQVNPI SKRMGPMTVV RMDASVQPGP FRTLLQFLYT GQLDEKEKDL VGLAQIAEVL EMFDLRMMVE NIMNKEAFMN QEITKAFHVR KANRIKECLS KGTFSDVTFK LDDGAISAHK PLLICSCEWM AAMFGGSFVE SANSEVYLPN INKISMQAVL DYLYTKQLSP NLDLDPLELI ALANRFCLPH LVALAEQHAV QELTKAATSG VGIDGEVLSY LELAQFHNAH QLAAWCLHHI CTNYNSVCSK FRKEIKSKSA DNQEYFERHR WPPVWYLKEE DHYQRVKRER EKEDIALNKH RSRRKWCFWN SSPAVA
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Molecular Weight
79.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RHOBTB1, a member of the Rho family of GTPases, has emerged as a significant factor in various cellular processes, including cell cycle regulation, cytoskeletal dynamics, and signal transduction. Research has indicated that RHOBTB1 may play a crucial role in tumor biology, particularly in cancer progression and metastasis. Its expression levels have been correlated with the malignancy of several tumors, suggesting that it could serve as a potential biomarker for cancer diagnosis or prognosis. Additionally, studies have shown that RHOBTB1 interacts with different proteins involved in tumor suppression and apoptosis, further highlighting its importance in maintaining cellular homeostasis. The recombinant protein form of RHOBTB1 is utilized in various experimental setups to elucidate its functional roles and mechanisms of action. By generating and characterizing RHOBTB1 recombinant proteins, researchers aim to better understand how this protein contributes to cellular processes and its implications in cancer and other diseases. This research could provide insights into novel therapeutic targets and strategies for intervention in RHOBTB1-related pathologies. Therefore, a deeper investigation into RHOBTB1's molecular pathways and interactions is essential for developing innovative approaches in cancer treatment and enhancing our overall understanding of cellular regulation.
