Analytical Data
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Gene name
RGL2
- Application
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Alternative Names
GDS related protein; HKE1.5; KE1.5; RAB2L; Ral guanine nucleotide dissociation stimulator-like 2; RalGDS-like 2; RalGDS-like factor; Ras-associated protein RAB2L; RGL2; RGL2_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15211
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Expression Region
1-777 aa
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AA Sequence
MLPRPLRLLL DTSPPGGVVL SSFRSRDPEE GGGPGGLVVG GGQEEEEEEE EEAPVSVWDE EEDGAVFTVT SRQYRPLDPL VPMPPPRSSR RLRAGTLEAL VRHLLDTRTS GTDVSFMSAF LATHRAFTST PALLGLMADR LEALESHPTD ELERTTEVAI SVLSTWLASH PEDFGSEAKG QLDRLESFLL QTGYAAGKGV GGGSADLIRN LRSRVDPQAP DLPKPLALPG DPPADPTDVL VFLADHLAEQ LTLLDAELFL NLIPSQCLGG LWGHRDRPGH SHLCPSVRAT VTQFNKVAGA VVSSVLGATS TGEGPGEVTI RPLRPPQRAR LLEKWIRVAE ECRLLRNFSS VYAVVSALQS SPIHRLRAAW GEATRDSLRV FSSLCQIFSE EDNYSQSREL LVQEVKLQSP LEPHSKKAPR SGSRGGGVVP YLGTFLKDLV MLDAASKDEL ENGYINFDKR RKEFAVLSEL RRLQNECRGY NLQPDHDIQR WLQGLRPLTE AQSHRVSCEV EPPGSSDPPA PRVLRPTLVI SQWTEVLGSV GVPTPLVSCD RPSTGGDEAP TTPAPLLTRL AQHMKWPSVS SLDSALESSP SLHSPADPSH LSPPASSPRP SRGHRRSASC GSPLSGGAEE ASGGTGYGGE GSGPGASDCR IIRVQMELGE DGSVYKSILV TSQDKAPSVI SRVLKKNNRD SAVASEYELV QLLPGERELT IPASANVFYA MDGASHDFLL RQRRRSSTAT PGVTSGPSAS GTPPSEGGGG SFPRIKATGR KIARALF
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Molecular Weight
83.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RGL2, or Regulator of G-protein signaling-like 2, is a member of the RGS (Regulator of G-protein signaling) family, which plays a crucial role in modulating G-protein-coupled receptor (GPCR) signaling pathways. The significance of RGL2 has garnered attention due to its potential impacts on various physiological processes and its involvement in certain diseases, including cancer and neurological disorders. Research into RGL2 has revealed that it may influence cellular signaling by acting as a molecular switch, thus regulating the intensity and duration of GPCR signaling. As a result, the study of RGL2 and its recombinant protein form is essential for understanding its biological functions and mechanisms. Recent advancements in protein expression and purification techniques have facilitated the generation of RGL2 recombinant proteins, providing valuable tools for in vitro studies aimed at elucidating its role in cellular signaling pathways. These studies not only enhance our understanding of RGL2's function but also hold promise for the development of novel therapeutic strategies targeting RGL2-related pathways. Therefore, ongoing research into RGL2 recombinant proteins is pivotal for both basic biological investigations and potential clinical applications.
