Analytical Data
-
Gene name
C8orf45
- Application
-
Alternative Names
MCMDC2; C8orf45Minichromosome maintenance domain-containing Protein 2; MCM domain-containing Protein 2
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q4G0Z9
-
Expression Region
1-681aa
-
AA Sequence
MSNLKMKEAA LIYLDRSGGL QKFIDDCKYY NDSKQSYAVY RFKILINPSD VVELDAELGN HILHQPLKAA EVFQSVCFIA VKTLSLIGQL QTETQINIVL KLTHLPPLPS YGLDLCEFPL DYTSQRFYMM QGIVIAMTTI TKYTQGARFL CSDEACPLSK GFQYIRVHVP GATESATIRN DFLCNLCASS LQEDRKFRVL GDKQIVEIIA TKALRAFQGY SNNQPFRFQS LTIFLRDESV NKMNIGNEYK IIGIPTCVKT SQTAVCIEAN SITFCNSKVP SGISDNFRCL LSLTSSSCWK FTAILANIFA SQITPPGTYN LLKLCLLMSL VQTTDRNKEL EDCLDILIIT SDTLLIDRLL NFSINLVPRG IRHLVSTEIF PTLSRNKYGT GAVSIQAGSA LLAKGGICFI GDLASHKKDK LEQLQTVLES RSITVYIPGK KFGEDIDQQM TFPVQCSFWS FVDVDSSSRR NAQKINTLIG QMDCSLIPAN LVEAFGLLIN CNESSPCHPF LPTVQHTLNK AINPEGLFYA ASRQFTTEDF EKLLAFAKNL NVEFSLEAER MTHGYYLASR RIRTGSVCGS KLSASALKYL VFLSEAHARL NLRNKVLKED VLIAALLFET SLTLKYGATV FCVAPNAVFP FELYNEEYLE QRDLYLTQCQ QQLEQFIATY GPGTTIFSSD E
-
Molecular Weight
76.2 KDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C8orf45, also known as Chromosome 8 Open Reading Frame 45, has garnered attention in recent years due to its potential roles in cellular functions and possible implications in disease mechanisms. This protein is located on chromosome 8 and is thought to be involved in various biological processes, including cell signaling and proliferation. Preliminary studies suggest that C8orf45 might play a role in certain cancers and other disorders, making it a candidate for further investigation. The characterization of C8orf45 as a recombinant protein is essential for understanding its structure-function relationship and elucidating its biological significance. In particular, generating high-purity recombinant C8orf45 can facilitate the analysis of its interaction with other cellular components and its functional roles within different cellular contexts. Additionally, studying this protein could provide insights into its potential as a biomarker or therapeutic target. The exploration of C8orf45 through recombinant protein technology also addresses the need for detailed studies on its expression patterns and post-translational modifications, which are critical for understanding how this protein operates under physiological and pathological conditions. Overall, the research surrounding C8orf45 recombinant protein is pivotal in expanding our knowledge of its biological roles and potential implications in human health and disease.
