Analytical Data
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基因名
C21orf25
- Application
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别名
C2 domain-containing Protein 2. Transmembrane Protein 24-like
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y426
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表达区间
1-388aa
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氨基酸序列
MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDILKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLLSEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKVPSWWLGRCSSGHLSVTCCSSAL
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分子量
68.42 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C21orf25, also known as chromosome 21 open reading frame 25, is a protein-coding gene located on human chromosome 21 that has garnered increasing interest due to its potential role in various biological processes and its association with Down syndrome, which is caused by an extra copy of chromosome 21. Research has indicated that C21orf25 may be involved in key cellular functions, including cell proliferation, differentiation, and apoptosis. Studies have suggested that alterations in the expression of C21orf25 could contribute to the phenotypic manifestations observed in individuals with Down syndrome, making it a candidate for further investigation in understanding the pathophysiology of this condition. Moreover, the protein's function and interactions remain largely unexplored, highlighting a critical gap in knowledge regarding its biological significance. Recombinant C21orf25 protein is being produced to facilitate in-depth studies, including its structural characterization, functional assays, and potential interactions with other cellular proteins. These investigations aim to elucidate the role of C21orf25 in cellular pathways and its implications in Down syndrome and related disorders, providing insights that could pave the way for novel therapeutic strategies. The development of this recombinant protein represents a promising step toward uncovering the underlying mechanisms of C21orf25 and its contribution to human health and disease.
