Analytical Data
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基因名
C21orf127
- Application
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别名
N6AMT1; C21orf127; HEMK2; PRED28; Methyltransferase N6AMT1; HemK methyltransferase family member 2; M.HsaHemK2P; Methylarsonite methyltransferase N6AMT1; EC 2.1.1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5N5
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表达区间
1-186aa
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氨基酸序列
MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLNALEAAAAELAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVGSHGIEAAWAGGKNGREVMDRFFPLVPDLLSPKGLFYLVTIKENNPEEILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS
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分子量
46.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C21orf127, also known as chromosome 21 open reading frame 127, is a relatively understudied gene that has gained attention in the context of various cellular processes and potential implications in diseases. Located on chromosome 21, this gene encodes a protein that is believed to have roles in cell proliferation, differentiation, and apoptosis. Recent studies have suggested that C21orf127 may be involved in the pathophysiology of Down syndrome, as it lies within a region of chromosome 21 that is triplicated in individuals with this condition. Its protein product has shown potential interactions with key signaling pathways and may influence neurodevelopmental outcomes. Given its localization and suggested functional roles, the recombinant expression and characterization of C21orf127 protein offer a promising avenue for elucidating its biological functions and exploring its impact in various diseases. Understanding the structure and function of the C21orf127 protein could provide insights into novel therapeutic targets, particularly for conditions associated with chromosome 21 abnormalities. Researchers are now focusing on producing recombinant C21orf127 protein to study its biochemical properties, interactions with other proteins, and functional roles in cellular mechanisms, thereby paving the way for future investigations into the therapeutic potential of modulating its activity in relevant disease contexts.
