Analytical Data
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基因名
RABEP2
- Application
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别名
FLJ23282; FRA; Rab GTPase binding effector protein 2; Rab GTPase-binding effector protein 2; Rabaptin 5 beta; Rabaptin RAB GTPase binding effector protein 2; Rabaptin-5beta; RABE2_HUMAN; RABEP 2; RABEP2; RABPT5B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H5N1
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表达区间
2-569 aa
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氨基酸序列
AAAAPVAAD DDERRRRPGA ALEDSRSQEG ANGEAESGEL SRLRAELAGA LAEMETMKAV AEVSESTKAE AVAAVQRQCQ EEVASLQAIL KDSISSYEAQ ITALKQERQQ QQQDCEEKER ELGRLKQLLS RAYPLDSLEK QMEKAHEDSE KLREIVLPME KEIEELKAKL LRAEELIQEI QRRPRHAPSL HGSTELLPLS RDPSPPLEPL EELSGDGGPA AEAFAHNCDD SASISSFSLG GGVGSSSSLP QSRQGLSPEQ EETASLVSTG TLVPEGIYLP PPGYQLVPDT QWEQLQTEGR QLQKDLESVS RERDELQEGL RRSNEDCAKQ MQVLLAQVQN SEQLLRTLQG TVSQAQERVQ LQMAELVTTH KCLHHEVKRL NEENQGLRAE QLPSSAPQGS QQEQGEEESL PSSVPELQQL LCCTRQEARA RLQAQEHGAE RLRIEIVTLR EALEEETVAR ASLEGQLRVQ REETEVLEAS LCSLRTEMER VQQEQSKAQL PDLLSEQRAK VLRLQAELET SEQVQRDFVR LSQALQVRLE RIRQAETLEQ VRSIMDEAPL TDVRDIKDT
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分子量
63.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RABEP2 (Rab ERP 2) is a member of the Rab family of small GTPases, which play crucial roles in regulating intracellular membrane trafficking and vesicle transport. This protein is primarily associated with the endosomal and recycling pathways, influencing cellular processes such as receptor recycling, endocytosis, and the maintenance of membrane organization. Research has indicated that RABEP2 is involved in various physiological functions, including neuronal signaling and synaptic transmission, which underscores its potential role in neurodevelopmental and neurodegenerative disorders. Moreover, dysregulation of RABEP2 has been linked to certain diseases, highlighting its significance in both health and disease contexts. As a result, recombinant RABEP2 protein has gained attention in scientific research, facilitating studies that explore its functional mechanisms and interactions at a molecular level. Understanding the structure and function of RABEP2 could provide insights into its contributions to cellular homeostasis and disease pathology, making it an important target for therapeutic interventions. The production of recombinant RABEP2 allows researchers to probe its biochemical properties and to investigate its role in cellular dynamics, thereby advancing our knowledge of membrane trafficking processes and their implications for human health.
