Analytical Data
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基因名
MT4
- Application
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别名
MT4；Metallothionein-4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P47944
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表达区间
1-62aa
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氨基酸序列
MDPRECVCMSGGICMCGDNCKCTTCNCKTYWKSCCPCCPPGCAKCARGCICKGGSDKCSCCP
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分子量
22.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MT4, or metallothionein 4, is a low-molecular-weight, cysteine-rich protein that plays a significant role in metal ion homeostasis and cellular stress responses. Initially identified in the context of heavy metal detoxification, MT4 has recently attracted attention for its potential roles in various physiological processes and pathologies, including neurodegenerative diseases and cancer. Research has shown that MT4 may participate in antioxidant defense, modulation of inflammation, and regulation of cell proliferation and apoptosis. Its expression is often tissue-specific, suggesting a tailored physiological function that is still not fully understood. The study of MT4 has been bolstered by advances in proteomics and molecular biology, which have facilitated the exploration of its structure, interaction with metals, and post-translational modifications. Additionally, the potential therapeutic applications of MT4 and its derivatives in clinical settings are currently being investigated, highlighting its importance in biomedical research and the need for further studies to elucidate its full biological significance.
