Analytical Data
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基因名
MT1A
- Application
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别名
MT1A；MT1S；Metallothionein-1A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04731
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表达区间
1-59aa
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氨基酸序列
MDPNCSCATGGSCTCTGSCKCKECKCTSCKKSCCSCCPMSCAKCAQGCICKGASEKCSC
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分子量
32.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MT1A (metallothionein 1A) is a member of the metallothionein family, which consists of low-molecular-weight proteins characterized by their high cysteine content and ability to bind metal ions. The primary function of MT1A is to regulate cellular metal homeostasis, detoxify heavy metals, and protect cells from oxidative stress. Research has indicated that MT1A plays a crucial role in various physiological processes, including metal ion transport, antioxidant defense, and cellular signaling. Dysregulation of MT1A expression has been linked to several diseases, including cancer, neurodegenerative disorders, and conditions related to metal toxicity. As a consequence, understanding the mechanisms governing MT1A expression and function is of significant interest in biomedical research. Scientists are exploring MT1A as a potential biomarker for disease progression and as a therapeutic target, particularly in the context of metal-related pathologies and oxidative stress-associated disorders. Additionally, advances in recombinant protein technology have facilitated the production of MT1A for structural and functional studies, providing insights into its interactions with various metal ions and its role in cellular mechanisms. Overall, the comprehensive study of MT1A is essential for elucidating its biological significance and potential applications in clinical settings.
