Analytical Data
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Gene name
TGOLN2
- Application
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Alternative Names
TGOLN2；TGN46；TGN51；Trans-Golgi network integral membrane Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43493
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Expression Region
22-381aa
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AA Sequence
ATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSS AEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKD STSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSE AQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGS NKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSD NKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDV EPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLY PNGSGNGSAEVDHHHHHH
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Molecular Weight
38 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TGOLN2, or Trans-Golgi Network Protein 2, is an essential protein involved in various cellular processes, particularly in the transport and sorting of proteins within the Golgi apparatus. Research on TGOLN2 has gained traction due to its pivotal role in maintaining cellular homeostasis and its implications in various diseases, including cancer and neurodegenerative disorders. Understanding the structure and function of TGOLN2 is crucial for elucidating its mechanism in vesicle trafficking, which is vital for proper cell function. Moreover, abnormalities in TGOLN2 expression or function can lead to disruptions in the Golgi network, contributing to pathological conditions. Recent studies have focused on the recombinant expression of TGOLN2 to facilitate detailed biochemical and structural analysis. This research not only enhances our comprehension of TGOLN2's role in cellular logistics but also paves the way for potential therapeutic interventions targeting Golgi-associated pathways. Overall, TGOLN2 represents a compelling target for further investigation aimed at deciphering its contributions to cell biology and disease pathology.
