Analytical Data
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Gene name
GNRH2
- Application
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Alternative Names
GNRH2；Progonadoliberin-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43555
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Expression Region
24-120aa
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AA Sequence
QHWSHGWYPGGKRALSSAQDPQNALRPPGRALDTAAGSPVQTAHGLPSDALAPLDDSMPWEGRTTAQWSLHRKRHLARTLLTAAREPRPAPPSSNKV
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Molecular Weight
26.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GNRH2, or Gonadotropin-Releasing Hormone 2, is a neuropeptide that plays a crucial role in the regulation of reproductive functions in various species. Discovered as a homolog of the well-studied GNRH1, GNRH2 is primarily involved in stimulating the release of gonadotropins, which are essential for the functioning of the reproductive system. Research on GNRH2 recombinant protein has gained attention due to its potential applications in understanding reproductive biology, treating infertility, and exploring its therapeutic uses in conditions such as hormone-dependent cancers. Studies have demonstrated that GNRH2 acts on distinct receptors compared to GNRH1, leading to different physiological responses, which further delineates its significance in various reproductive processes. Furthermore, the ability to produce GNRH2 as a recombinant protein facilitates the exploration of its structural and functional characteristics, allowing for detailed studies on its interactions with receptors and effects on downstream signaling pathways. This has implications not only for basic reproductive physiology but also for developing novel therapies in reproductive health and oncology. Overall, the investigation of GNRH2 as a recombinant protein is pivotal in broadening our understanding of neuropeptide signaling in reproduction and its potential clinical applications.
