Analytical Data
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基因名
TRAT1
- Application
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别名
TRAT1；TCRIM；T-cell receptor-associated transmembrane adapter 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6PIZ9
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表达区间
29-186aa
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氨基酸序列
MNISHYVEKQRQDKMYSYSSDHTRVDEYYIEDTPIYGNLDDMISEPMDEN CYEQMKARPEKSVNKMQEATPSAQATNETQMCYASLDHSVKGKRRKPRKQ NTHFSDKDGDEQLHAIDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGL IRAKREPIN
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分子量
19 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRAT1, or T cell receptor-associated transducer protein 1, is a key regulator in T cell signaling pathways and immune responses. Research on TRAT1 has gained momentum due to its potential role in modulating T cell activation and differentiation, which are crucial in both adaptive immunity and various immunological disorders. TRAT1 is implicated in several essential processes, such as the assembly of the T cell receptor complex and the trafficking of signaling molecules within T cells. Recent studies have shown that its dysregulation may contribute to autoimmune diseases, chronic infections, and cancer progression, making it a target of interest for therapeutic interventions. Understanding the structure and function of TRAT1, especially through the production and characterization of its recombinant protein, could provide insights into its mechanisms of action and offer novel strategies for manipulating immune responses. Additionally, investigating TRAT1's interactions with other proteins and its involvement in signaling pathways may reveal potential biomarkers for disease states and therapeutic targets. As research in this area advances, TRAT1 continues to emerge as a significant player in immunology, highlighting the importance of studying its recombinant forms to pave the way for future applications in immunotherapy and vaccine development.
