Analytical Data
-
Gene name
EphA6
- Application
-
Alternative Names
EphA6；EHK2；HEK12；Ephrin type-A receptor 6
-
Species
Mouse
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q62413
-
Expression Region
1-546aa
-
AA Sequence
MGGCEVREFL LQFGFFLPLL TAWTGDCSHV SNQVVLLDTT TVMGELGWKT YPLNGWDAIT EMDEHNRPIH TYQVCNVMEP NQNNWLRTNW ISRDAAQKIY VEMKFTLRDC NSIPWVLGTCKETFNLYYI ESDESHGTKF KPSQYIKIDT IAADESFTQM DLGDRILKLN TEIREVGPIE RKGFYLAFQD IGACIALVSV RVFYKKCPFT VRNLAMFPDT IPRVDSSSLV EVRGSCVKSA EERDTPKLYC GADGDWLVPL GRCICSTGYE EIEGSCHACR PGFYKAFAGN TKCSKCPPHS STYVEATSVC HCEKGYFRAE KDPPSMACTR PPSAPRNVAF NINETALILE WSPPSDTGGR KDLTYSVICK KCGLDTTQCE DCGGGLRFIP RHTGLINNSV VVLDFVSHVN YTFEIEAMNG VSELSISPKP FTAITVTTDH DAPSLIGMMR KDWASQNSLA LSWQAPAFSN GAILDYEIKY YEKEHEQLTY SSTRSKAPSV IVTGLKPATT YIFHIRVRTA TGYSGYSQKF EFETGDETSD MAAEQGQ
-
Molecular Weight
60 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EphA6 is a member of the Eph receptor tyrosine kinase family, which plays crucial roles in various biological processes, including cell migration, differentiation, and the establishment of neuronal connections. It is primarily expressed in the central nervous system and has been linked to neurodevelopmental processes and synaptic functions. Recent studies suggest that alterations in EphA6 expression or function may be associated with various neurological disorders, including schizophrenia and autism spectrum disorders. To better understand the biological functions of EphA6 and its potential implications in these diseases, researchers have focused on the development of recombinant EphA6 proteins. Such proteins allow for detailed investigations of EphA6 signaling pathways, interactions with ephrin ligands, and their roles in modulating neuronal behavior. Additionally, the availability of recombinant EphA6 can facilitate the search for potential therapeutic targets and biomolecular interventions that could ameliorate the effects of its dysregulation. Through the elucidation of EphA6's structure and function, researchers aim to uncover novel insights into its contributions to neurobiology and its relevance in the context of mental health.
