Cat: PA1000-4452

Recombinant Human PRG3 Protein,His

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Analytical Data

  • Gene name

    PRG3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    PRG3;MBPH;Proteoglycan 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9Y2Y8

  • Expression Region

    18-225aa

  • AA Sequence

    LHL ENDAPHLESL ETQADLGQDL DSSKEQERDL ALTEEVIQAE GEEVKASACQ DNFEDEEAME SDPAALDKDF QCPREEDIVE VQGSPRCKIC RYLLVRTPKT FAEAQNVCSR CYGGNLVSIH DFNFNYRIQC CTSTVNQAQV WIGGNLRGWF LWKRFCWTDG SHWNFAYWSP GQPGNGQGSC VALCTKGGYW RRAQCDKQLP FVCSF

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

PRG3 (Progestogen-Associated Endometrial Protein 3) is a member of the lipocalin family, primarily expressed in human endometrial tissues, and is associated with reproductive functions. Its expression is modulated by hormonal signals, particularly during the menstrual cycle and pregnancy, indicating a potential role in reproductive health and early embryo development. The study of PRG3 recombinant proteins has gained traction in recent years, driven by the need to understand its biological functions and mechanisms at a molecular level. Research has suggested that PRG3 may play a role in immune modulation within the endometrium, contributing to a favorable environment for embryo implantation and maintenance of pregnancy. The recombinant form of PRG3 allows for detailed biochemical analysis and functional assays, enabling scientists to explore its interactions with other proteins and molecules involved in reproductive processes. This research has potential implications for addressing fertility issues and developing new therapeutic strategies for reproductive disorders. Furthermore, understanding PRG3’s properties may pave the way for novel contraceptives or treatments for conditions like endometriosis, underscoring the importance of continued investigations into this significant biomolecule. Overall, the study of PRG3 recombinant proteins represents a promising avenue in reproductive biology that could enhance our understanding of fertility and related health issues.

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