Cat: PA2000-1875

Recombinant Human ADTRP Protein,His

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Analytical Data

  • Gene name

    ADTRP

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ADTRP;C6orf105;Androgen-dependent TFPI-regulating Protein

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q96IZ2

  • Expression Region

    1-230aa

  • AA Sequence

    MTKTSTCIYH FLVLSWYTFL NYYISQEGKD EVKPKILANG ARWKYMTLLN LLLQTIFYGV TCLDDVLKRT KGGKDIKFLT AFRDLLFTTL AFPVSTFVFL AFWILFLYNR DLIYPKVLDT VIPVWLNHAM HTFIFPITLA EVVLRPHSYP SKKTGLTLLA AASIAYISRI LWLYFETGTW VYPVFAKLSL LGLAAFFSLS YVFIASIYLL GEKLNHWKWG DMRQPRKKRK

  • Molecular Weight

    32 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ADTRP (Adipose-Derived Tissue Regulator Protein) is a protein that has garnered significant attention in the field of molecular biology and medicine due to its crucial role in adipose tissue regulation and cardiovascular health. Research indicates that ADTRP is involved in various physiological processes, including adipogenesis and inflammation, which are vital for maintaining metabolic homeostasis. Dysregulation of adipose tissue function is implicated in obesity-related disorders, such as insulin resistance and hypertension. Consequently, understanding the molecular mechanisms governing ADTRP functionality may provide insights into potential therapeutic targets for treating metabolic diseases. Moreover, studies have suggested that ADTRP might influence vascular smooth muscle cell proliferation and migration, linking it to vascular remodeling and cardiovascular disease progression. As such, the exploration of ADTRP as a recombined protein offers promising avenues for research aimed at unraveling its biological significance and therapeutic potential. Researchers are focusing on the recombinant expression of ADTRP to study its structure-function relationships and interaction with other signaling pathways. This knowledge could pave the way for novel approaches to mitigate the adverse effects of metabolic disorders and improve overall cardiovascular health.

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