Analytical Data
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Gene name
NTNG1
- Application
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Alternative Names
NTNG1；KIAA0976；Netrin-G1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y2I2-1
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Expression Region
1-408aa
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AA Sequence
MYLSRFLSIH ALWVTVSSVM QPYPLVWGHY DLCKTQIYTE EGKVWDYMAC QPESTDMTKY LKVKLDPPDI TCGDPPETFC AMGNPYMCNN ECDASTPELA HPPELMFDFE GRHPSTFWQS ATWKEYPKPL QVNITLSWSK TIELTDNIVI TFESGRPDQM ILEKSLDYGR TWQPYQYYAT DCLDAFHMDP KSVKDLSQHT VLEIICTEEY STGYTTNSKI IHFEIKDRFA FFAGPRLRNM ASLYGQLDTT KKLRDFFTVT DLRIRLLRPA VGEIFVDELH LARYFYAISD IKVRGRCKCN LHATVCVYDN SKLTCECEHN TTGPDCGKCK KNYQGRPWSP GSYLPIPKGT ANTCIPSISS IGTNVCDNEL LHCQNGGTCH NNVRCLCPAA YTGILCEKLR CEEAGSCG
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Molecular Weight
46 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NTNG1 (Netrin G1) is a protein that belongs to the netrin family, known for its role in neuronal development and synaptic functions. Research into NTNG1 has garnered significant interest due to its involvement in guiding neuronal growth cones, regulating synaptic formation, and influencing neuronal connections in the brain. Abnormalities in NTNG1 expression or function have been implicated in various neurological disorders, including schizophrenia and autism spectrum disorders, highlighting its importance in understanding neurodevelopmental processes. Recent studies have focused on the biochemical properties of NTNG1, investigating its interactions with receptors and other cellular components, which contribute to its signaling pathways. The recombinant expression of NTNG1 in laboratory settings has allowed researchers to analyze its functional characteristics and therapeutic potentials. By producing NTNG1 as a recombinant protein, scientists can study its structure-function relationships, elucidate its mechanisms of action, and explore its possible role as a biomarker or therapeutic target in neurological diseases. This growing body of research underscores the significance of NTNG1 in neuroscience and its potential applications in developing innovative treatments for devastating neurodegenerative conditions. Additionally, understanding the biological implications of NTNG1 can pave the way for advancements in regenerative medicine and neurobiology, contributing to the broader field of neuronal repair and cognitive function restoration.
