Analytical Data
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Gene name
PRDX5
- Application
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Alternative Names
PRDX5；ACR1；Peroxiredoxin-5. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P30044
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Expression Region
53-214aa
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AA Sequence
MAPIKVGD AIPAVEVFEG EPGNKVNLAE LFKGKKGVLF GVPGAFTPGC SKTHLPGFVE QAEALKAKGV QVVACLSVND AFVTGEWGRA HKAEGKVRLL ADPTGAFGKE TDLLLDDSLV SIFGNRRLKR FSMVVQDGIV KALNVEPDGT GLTCSLAPNI ISQL
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Peroxiredoxin 5 (PRDX5) is a member of the peroxiredoxin family, which plays a pivotal role in cellular redox regulation and antioxidant defense. It is primarily localized in the mitochondria and cytosol, functioning as a scavenger of reactive oxygen species (ROS), thereby mitigating oxidative stress and maintaining cellular homeostasis. Research on PRDX5 has gained momentum due to its implications in various biological processes, including cell proliferation, apoptosis, and inflammation. Dysregulation of PRDX5 has been associated with several diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases, indicating its potential as a therapeutic target. Recent studies have focused on the recombinant expression of PRDX5 to elucidate its functional mechanisms and structure-function relationships, as well as to explore its therapeutic applications. By producing recombinant PRDX5, researchers aim to gain insights into its enzymatic properties and interactions with other molecular partners, enabling a deeper understanding of its role in oxidative stress response and disease pathology. Furthermore, the availability of recombinant PRDX5 opens up opportunities for the development of novel antioxidant therapies and diagnostic tools, highlighting the significance of ongoing research in this area. As the understanding of PRDX5 continues to evolve, it remains a promising candidate for exploration in the context of aging, inflammation, and various oxidative stress-related conditions.
