Analytical Data
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Gene name
ZC4H2
- Application
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Alternative Names
ZC4H2；HCA127；Zinc finger C4H2 domain-containing Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NQZ6
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Expression Region
1-224aa
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AA Sequence
MADEQEIMCK LESIKEIRNK TLQMEKIKAR LKAEFEALES EERHLKEYKQ EMDLLLQEKM AHVEELRLIH ADINVMENTI KQSENDLNKL LESTRRLHDE YKPLKEHVDA LRMTLGLQRL PDLCEEEEKL SLDYFEKQKA EWQTEPQEPP IPESLAAAAA AAQQLQVARK QDTRQTATFR QQPPPMKACL SCHQQIHRNA PICPLCKAKS RSRNPKKPKR KQDE
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZC4H2, a member of the zinc finger-containing proteins family, is implicated in various biological processes, including gene regulation, cellular response to stress, and immune function. Mutations or dysregulation of ZC4H2 have been linked to several disease states, particularly neurodevelopmental disorders, highlighting its potential role in cognitive function and neurological health. Research into ZC4H2 fusion proteins has gained traction, particularly in the context of cancer biology, where its fusion variants are associated with specific tumor types, suggesting aberrant signaling pathways that drive oncogenesis. Understanding the structural and functional characteristics of recombinant ZC4H2 proteins is critical for elucidating their molecular mechanisms and therapeutic potentials. The production of ZC4H2 recombinant proteins allows for detailed investigations into their biochemical properties, interactions with other cellular molecules, and roles in gene expression and signaling pathways. By utilizing advanced techniques such as protein purification, crystallography, and functional assays, researchers aim to clarify the contributions of ZC4H2 to health and disease, paving the way for innovative therapeutic strategies targeting ZC4H2-related conditions. This research is essential not only for advancing our understanding of fundamental biological processes but also for addressing the clinical implications of ZC4H2 dysregulation in various diseases.
