Analytical Data
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Gene name
ZADH2
- Application
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Alternative Names
ZADH2；ZADH2；Prostaglandin reductase 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N4Q0
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Expression Region
33-377aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSMQKLVVTRLSPNFREAVTLSRDCPVPL PGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGL SASARYTVGQAVAYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGTT AYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEK SAFLKSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDA LATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYL SKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIFRAVNYMYMG KNTGKIVVELPHSVNSKL
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Molecular Weight
39 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZADH2, a member of the zinc finger protein family, has garnered attention in the field of molecular biology due to its potential role in various cellular processes, including gene regulation, DNA repair, and cell cycle control. Initially identified as a protein associated with zinc finger domains, ZADH2 is believed to be implicated in post-translational modifications and the response to oxidative stress, which are critical for maintaining cellular homeostasis. The understanding of ZADH2's function has significant implications, particularly in the context of cancer research and other diseases where dysregulation of these processes is observed. Recombinant protein studies of ZADH2 facilitate the exploration of its biochemical properties, interaction partners, and functional mechanisms within the cell. By producing ZADH2 in a controlled laboratory setting, researchers aim to elucidate its contributions to cellular pathways and assess its potential as a therapeutic target or biomarker. Furthermore, studies involving ZADH2 can provide insights into the intricate network of protein interactions central to cellular function, making it a valuable focus of research in understanding complex biological systems and disease mechanisms.
