Analytical Data
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Gene name
PHACTR2
- Application
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Alternative Names
PHACTR2; C6orf56; KIAA0680; Phosphatase and actin regulator 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75167
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Expression Region
1-634 aa
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AA Sequence
MDNAVDGLDK ASIANSDGPT AGSQTPPFKR KGKLSTIGKI FKPWKWRKKK TSDKFRETSA VLERKISTRQ SREELIRRGV LKELPDQDGD VTVNFENSNG HMIPIGEEST REENVVKSEE GNGSVSEKTP PLEEQAEDKK ENTENHSETP AAPALPPSAP PKPRPKPKPK KSPVPPKGAT AGASHKGDEV PPIKKNTKAP GKQAPVPPPK PASRNTTREA AGSSHSKKTT GSKASASPST SSTSSRPKAS KETVSSKAGT VGTTKGKRKT DKQPITSHLS SDTTTSGTSD LKGEPAETRV ESFKLEQTVP GAEEQNTGKF KSMVPPPPVA PAPSPLAPPL PLEDQCITAS DTPVVLVSVG ADLPVSALDP SQLLWAEEPT NRTTLYSGTG LSVNRENAKC FTTKEELGKT VPQLLTPGLM GESSESFSAS EDEGHREYQA NDSDSDGPIL YTDDEDEDED EDGSGESALA SKIRRRDTLA IKLGNRPSKK ELEDKNILQR TSEEERQEIR QQIGTKLVRR LSQRPTTEEL EQRNILKQKN EEEEQEAKME LKRRLSRKLS LRPTVAELQA RRILRFNEYV EVTDSPDYDR RADKPWARLT PADKAAIRKE LNEFKSTEME VHEESRQFTR FHRP
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Molecular Weight
69.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PHACTR2 (Phosphatase and Actin Regulator 2) is a protein that plays a significant role in various cellular processes, including cytoskeletal dynamics, cell signaling, and proliferation. Recent research indicates that PHACTR2 is involved in molecular pathways linked to neuronal functions and has potential implications in the pathology of neurodegenerative diseases. The protein modulates actin filament assembly and disassembly, which is crucial for the maintenance of cell shape and motility. Furthermore, dysregulation of PHACTR2 has been associated with several disorders, highlighting its importance in health and disease. As a result, the recombinant PHACTR2 protein has become a focus of study for understanding its structural and functional properties, enabling researchers to elucidate its biological roles. Characterizing the recombinant form of PHACTR2 can lead to insights into its mechanisms of action and how it interacts with other cellular components. This knowledge may pave the way for potential therapeutic strategies targeting PHACTR2-related pathways in various diseases, including cancer and neurological disorders. The ongoing investigation into PHACTR2 and its recombinant protein forms is critical for the development of novel interventions that could enhance treatment outcomes and improve patient care in conditions where PHACTR2 is implicated.
