Cat: PAX2000-10269

Recombinant Human PGS1 Protein,His

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Analytical Data

  • Gene name

    PGS1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CDP diacylglycerol glycerol 3 phosphate 3 phosphatidyltransferase mitochondrial; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; HCG1642326. isoform CRA_b; mitochondrial; PGP synthase 1; PGPS1_HUMAN; PGS1; PGS1 protein Fragment; Phosphatidylglycerophosphate synthase 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q32NB8

  • Expression Region

    29-556 aa

  • AA Sequence

    AL LGRLSDRLGR NRDRQRRRSP WLLLAPLLSP AVPQVTSPPC CLCPEGVHRF QWIRNLVPEF GVSSSHVRVL SSPAEFFELM KGQIRVAKRR VVMASLYLGT GPLEQELVDC LESTLEKSLQ AKFPSNLKVS ILLDFTRGSR GRKNSRTMLL PLLRRFPEQV RVSLFHTPHL RGLLRLLIPE RFNETIGLQH IKVYLFDNSV ILSGANLSDS YFTNRQDRYV FLQDCAEIAD FFTELVDAVG DVSLQLQGDD TVQVVDGMVH PYKGDRAEYC KAANKRVMDV INSARTRQQM LHAQTFHSNS LLTQEDAAAA GDRRPAPDTW IYPLIQMKPF EIQIDEIVTE TLLTEAERGA KVYLTTGYFN LTQAYMDLVL GTRAEYQILL ASPEVNGFFG AKGVAGAIPA AYVHIERQFF SEVCSLGQQE RVQLQEYWRR GWTFHAKGLW LYLAGSSLPC LTLIGSPNFG YRSVHRDLEA QIAIVTENQA LQQQLHQEQE QLYLRSGVVS SATFEQPSRQ VKLWVKMVTP LIKNFF

  • Molecular Weight

    62.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

PGS1 (Phosphatidylglycerol Synthase 1) is an essential enzyme involved in the biosynthesis of phosphatidylglycerol, a crucial component of cellular membranes in various organisms, particularly in bacteria and plants. Understanding PGS1's structure and function is vital due to its role in maintaining membrane integrity and fluidity, which directly impacts cell growth, division, and overall health. Moreover, in plants, phosphatidylglycerol is involved in the biosynthesis of chloroplast membranes, influencing photosynthesis and energy metabolism. Research into PGS1 recombinant proteins has gained traction as scientists aim to elucidate its mechanisms, identify potential regulation pathways, and explore its interactions with other cellular components. Advances in recombinant DNA technology and protein expression systems have facilitated the production of PGS1 in heterologous systems, allowing for detailed biochemical characterization. This research not only sheds light on fundamental cellular processes but also opens avenues for biotechnological applications, such as the development of stress-resistant crops or novel antimicrobial agents. Furthermore, understanding PGS1 may provide insights into related pathways in pathogenic organisms, unlocking potential strategies for combatting diseases. As the demand for sustainable agricultural practices and innovative therapeutics grows, the study of PGS1 and its recombinant forms continues to be a pertinent focus within the fields of biochemistry, molecular biology, and agricultural sciences.

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