Analytical Data
-
基因名
ATP6V1G1
- Application
-
别名
ATP 6G; ATP 6J; ATP6G; ATP6G1; ATP6GL; Atp6v1g1; ATPase H+ transporting lysosomal (vacuolar proton pump) member J
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O75348
-
表达区间
2-118aa
-
氨基酸序列
ASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSRGSCSTEVEKETQEKMTILQTYFRQNRDEVLDNLLAFVCDIRPEIHENYRING
-
分子量
40.6kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ATP6V1G1 is a critical gene encoding a subunit of the vacuolar ATPase (V-ATPase) complex, which is essential for acidifying various intracellular compartments, including lysosomes and endosomes. This process is vital for numerous cellular functions, such as protein degradation, nutrient sensing, and regulation of cellular pH. Recent studies have revealed that ATP6V1G1 plays a significant role in various physiological and pathological processes, including cancer progression, where altered expression of V-ATPase components can affect tumor microenvironment and metastasis. Understanding the function of ATP6V1G1 and its protein interactions can provide insights into the mechanisms by which V-ATPase contributes to disease states. Additionally, given its involvement in cellular signaling pathways, research on ATP6V1G1 may unveil novel therapeutic targets for conditions characterized by V-ATPase dysregulation. The recombinant expression of ATP6V1G1 protein is crucial for functional studies, allowing researchers to delineate its role and potential as a biomarker or a therapeutic target. By employing techniques like gene cloning, prokaryotic, or eukaryotic expression systems, scientists aim to produce sufficient amounts of this protein for detailed biochemical and structural characterization. Furthermore, understanding the implication of ATP6V1G1 in various cellular processes can aid in the development of strategies for targeting V-ATPase activity in diseases where its regulation is compromised. Overall, ATP6V1G1 represents an important focus for ongoing research aiming to unravel the complexities of cellular acidification and its broader implications in health and disease.












