Analytical Data
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基因名
ASB10
- Application
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别名
ASB10Ankyrin repeat and SOCS box Protein 10; ASB-10
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WXI3
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表达区间
1-467aa
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氨基酸序列
MLMSWSPEEC KGQGEPLDDR HPLCARLVEK PSRGSEEHLK SGPGPIVTRT ASGPALAFWQ AVLAGDVGCV SRILADSSTG LAPDSVFDTS DPERWRDFRF NIRALRLWSL TYEEELTTPL HVAASRGHTE VLRLLLRRRA RPDSAPGGRT ALHEACAAGH TACVHVLLVA GADPNIADQD GKRPLHLCRG PGTLECAELL LRFGARVDGR SEEEEETPLH VAARLGHVEL ADLLLRRGAC PDARNAEGWT PLLAACDVRC QSITDAEATT ARCLQLCSLL LSAGADADAA DQDKQRPLHL ACRRGHAAVV ELLLSCGVSA NTMDYGGHTP LHCALQGPAA ALAQSPEHVV RALLNHGAVR VWPGALPKVL ERWSTCPRTI EVLMNTYSVV QLPEEAVGLV TPETLQKHQR FYSSLFALVR QPRSLQHLSR CALRSHLEGS LPQALPRLPL PPRLLRYLQL DFEGVLY
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分子量
51.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The ASB10 protein, a member of the ankyrin repeat and SOCS box-containing protein family, has garnered attention in recent years due to its potential role in regulating various cellular processes, including protein degradation and signal transduction. Research indicates that ASB10 may play a significant role in the modulation of immune responses and the regulation of inflammation, suggesting its importance in diseases such as cancer and autoimmune disorders. Moreover, ASB10 has been implicated in the ubiquitin-proteasome system, where it may function as an E3 ubiquitin ligase, tagging specific substrates for degradation. This activity is crucial in maintaining cellular homeostasis and responding to stressors. As such, recombinant forms of ASB10 have been developed for detailed studies to elucidate its functional properties and biochemical mechanisms. The generation of ASB10 recombinant proteins not only facilitates the exploration of its interaction with other cellular components but also aids in the development of potential therapeutic interventions targeting dysfunctional pathways associated with ASB10. In summary, the ongoing research into ASB10 and its recombinant proteins is pivotal in advancing our understanding of its biological significance and therapeutic potential in various health conditions.
