Cat: PA2000-5616

Recombinant Human ARMC8 Protein,GST

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Analytical Data

  • Gene name

    ARMC8

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Armadillo repeat containing Protein 8; Armadillo repeat-containing Protein 8; ARMC8; ARMC8_HUMAN; HSPC056; MGC10058; MGC4880; S863 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8IUR7

  • Expression Region

    2-673aa

  • AA Sequence

    ACLLETPIR MSVLSEVTAS SRHYVDRLFD PDPQKVLQGV IDMKNAVIGN NKQKANLIVL GAVPRLLYLL QQETSSTELK TECAVVLGSL AMGTENNVKS LLDCHIIPAL LQGLLSPDLK FIEACLRCLR TIFTSPVTPE ELLYTDATVI PHLMALLSRS RYTQEYICQI FSHCCKGPDH QTILFNHGAV QNIAHLLTSL SYKVRMQALK CFSVLAFENP QVSMTLVNVL VDGELLPQIF VKMLQRDKPI EMQLTSAKCL TYMCRAGAIR TDDNCIVLKT LPCLVRMCSK ERLLEERVEG AETLAYLIEP DVELQRIASI TDHLIAMLAD YFKYPSSVSA ITDIKRLDHD LKHAHELRQA AFKLYASLGA NDEDIRKKII ETENMMDRIV TGLSESSVKV RLAAVRCLHS LSRSVQQLRT SFQDHAVWKP LMKVLQNAPD EILVVASSML CNLLLEFSPS KEPILESGAV ELLCGLTQSE NPALRVNGIW ALMNMAFQAE QKIKADILRS LSTEQLFRLL SDSDLNVLMK TLGLLRNLLS TRPHIDKIMS THGKQIMQAV TLILEGEHNI EVKEQTLCIL ANIADGTTAK DLIMTNDDIL QKIKYYMGHS HVKLQLAAMF CISNLIWNEE EGSQERQDKL RDMGIVDILH KLSQSPDSNL CDKAKMALQQ YLA

  • Molecular Weight

    75 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ARMC8 (Armadillo Repeat Molecule 8) is a protein that has garnered significant interest in recent years due to its potential roles in various biological processes and diseases. Initially identified as a member of the armadillo repeat superfamily, ARMC8 is implicated in cellular signaling, protein-protein interactions, and the regulation of developmental processes. Research has indicated that ARMC8 may play a crucial role in cancer biology, particularly in the context of tumor progression and metastasis. It has been observed that ARMC8 interacts with other key proteins involved in cellular pathways, suggesting its influence on cell proliferation and apoptosis. Moreover, studies have indicated that alterations in ARMC8 expression can affect cellular responses to stress and contribute to the onset of certain pathological conditions. Consequently, the recombinant expression of ARMC8 has become a focal point for researchers aiming to elucidate its functional mechanisms and therapeutic potentials. Investigating the structure and function of ARMC8 through recombinant protein studies can provide valuable insights into its biological roles and potential as a target for drug development, particularly in cancer therapy. As ongoing research continues to reveal the complexities of ARMC8's interactions and functions, it presents an exciting avenue for understanding its implications in health and disease.

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