Analytical Data
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Gene name
CDH20
- Application
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Alternative Names
CDH20；CDH7L3；Cadherin-20
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HBT6
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Expression Region
35-619aa
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AA Sequence
DTPTPQGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSR
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Molecular Weight
66.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CDH20, a member of the cadherin family of cell adhesion molecules, plays a crucial role in maintaining cell-cell interactions and tissue architecture. The study of CDH20 is gaining importance due to its involvement in various biological processes, including embryonic development, tissue differentiation, and the maintenance of epithelial integrity. Dysregulation of cadherins, including CDH20, has been implicated in numerous pathological conditions, particularly in cancer metastasis and progression, where altered cell adhesion can lead to increased migratory and invasive properties of tumor cells. Furthermore, CDH20 has been explored as a potential biomarker for certain cancers, making it a target of interest in research aimed at understanding cancer biology and developing therapeutic strategies. Investigating the recombinant expression of CDH20 allows researchers to delve deeper into its functional mechanisms and interactions with other cellular components, potentially revealing novel therapeutic avenues. The recombinant protein provides a valuable tool for in vitro studies, enabling the analysis of its role in cell adhesion and signaling pathways in a controlled environment. Overall, the study of CDH20 recombinant protein is pivotal for unraveling the complexities of cell adhesion dynamics and its implications in health and disease.
