Analytical Data
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基因名
TMOD3
- Application
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别名
TMOD3；Tropomodulin-3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NYL9
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表达区间
1-352aa
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氨基酸序列
MALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYVPYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVFDEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGDHQ
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分子量
66.6kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMOD3, or Tropomodulin 3, is a member of the tropomodulin family of proteins, known for their role in regulating actin filament stability and length in muscle and non-muscle cells. These proteins are pivotal in maintaining the integrity of the cytoskeleton, which is essential for various cellular processes including motility, division, and intracellular transport. The study of TMOD3 is particularly relevant in the context of cardiovascular health, as it is involved in cardiac muscle function and may have implications in heart-related diseases. Recent research has indicated that aberrations in TMOD3 expression or function can contribute to muscle disorders, highlighting the importance of understanding its molecular mechanisms. The generation of recombinant TMOD3 proteins facilitates the exploration of its structure-function relationships and potential interactions with other cytoskeletal components. This can provide insights into the regulatory pathways that involve TMOD3, which could ultimately lead to novel therapeutic strategies for muscle-related diseases. Overall, the investigation of TMOD3 recombinant proteins serves as a crucial step in elucidating their biological roles and therapeutic potential in cardiovascular and musculoskeletal disorders.
